2020•PubMedOpen access

[Analysis of immunophenotypes and expressions of non-myeloid antigens in acute myeloid leukemia].

Weiwei Wang, Yuanhong Xu

Abstract

OBJECTIVE: To investigate the characteristics of immunophenotypes and expressions of non-myeloid differentiation antigens in acute myeloid leukemia (AML) and their value in diagnosis and prognostic evaluation of AML. METHODS: We examined the immunophenotypes of 109 patients with AML using BD FACSCalibur flow cytometry and analyzed the association of the immunophenotypes and expressions of non-myeloid differentiation antigens with the prognosis and complete remission (CR) rate of the patients. RESULTS: < 0.05). CONCLUSIONS: Immunophenotyping and analysis of non-myeloid differentiation antigens can be of great clinical significance for the diagnosis and prognostic evaluation of AML, and serve also as one of the important bases for the diagnosis and treatment of AML.

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Available abstract

Key concepts: CD33, Immunophenotyping, Myeloid leukemia, Myeloid, CD117, CD15, Antigen, CD34