2019Unpublished venueOpen access

Nanopore sequencing: The fourth generation sequencing

Abhay Kumar, Kumar, Vinay, Prafulla Kumar

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Abstract

DNA is a molecule that makes up the genetic material of a cell, and it is responsible for carrying the information needed for survival, growth, and reproduction of an organism. DNA sequencing is the process of determining this sequence of nucleotides. Originally sequencing was an expensive process, but during the last couple of decades, the price of sequencing has drastically decreased. A significant breakthrough occurred in May 2015 with the release of MinION sequencer by Oxford Nanopore making DNA sequencing inexpensive and more available, even for small research teams. This review condensed various nanopore based sequencer utilized for DNA sequencing and currently available developed technologies in the market and under development technology for biomolecules sequencing.

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What this paper is about

DNA is a molecule that makes up the genetic material of a cell, and it is responsible for carrying the information needed for survival, growth, and reproduction of an organism. DNA sequencing is the process of determining this sequence of nucleotides. Originally sequencing was an expensive process, but during the last couple of decades, the price of sequencing has drastically decreased. A significant breakthrough occurred in May 2015 with the release of MinION sequencer by Oxford Nanopore making DNA sequencing inexpensive and more available, even for small research teams. This review condensed various nanopore based sequencer utilized for DNA sequencing and currently available developed technologies in the market and under development technology for biomolecules sequencing.

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Available abstract

DNA is a molecule that makes up the genetic material of a cell, and it is responsible for carrying the information needed for survival, growth, and reproduction of an organism. DNA sequencing is the process of determining this sequence of nucleotides. Originally sequencing was an expensive process, but during the last couple of decades, the price of sequencing has drastically decreased. A significant breakthrough occurred in May 2015 with the release of MinION sequencer by Oxford Nanopore making DNA sequencing inexpensive and more available, even for small research teams. This review condensed various nanopore based sequencer utilized for DNA sequencing and currently available developed technologies in the market and under development technology for biomolecules sequencing.

Key concepts: Minion, Nanopore sequencing, DNA sequencing, Nanopore, DNA sequencer, Biology, DNA, Computational biology

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