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2020•Research Journal of Pharmacy and TechnologyRequires access

Evaluation the serum vascular endothelial growth factor C (VEGF-C) value in breast cancer patients

Amani Assaf, Jumana Alsaleh

Open publisher page 3 citations

Abstract

BackgroundBreast cancer is the second most common cancer in females. VEGF-C overexpression has been reported in breast cancer patients, and correlates with metastasis and poor prognosis. Objective: Determination the serum VEGF-C concentration in breast cancer patients, and its change after treatment.MethodologyThis is a prospective, cross sectional study, include 65 women (30 with breast cancer, 35 healthy) met the study criteria. the serum VEGF-C values were measured at the beginning and after finishing the treatment.ResultsThere is no differences in age between two groups, The mean of serum VEGF-C values was higher in breast cancer patients (1122.74±853.97 U/L vs 334.55±522.6 U/L; P<0.00),. Serum VEGF-C level was significantly higher in breast cancer patients before the treatment compared with after treatment (P <0.01).Serum VEGF-C value has a good correlation with breast cancer.

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What this paper is about

BackgroundBreast cancer is the second most common cancer in females. VEGF-C overexpression has been reported in breast cancer patients, and correlates with metastasis and poor prognosis. Objective: Determination the serum VEGF-C concentration in breast cancer patients, and its change after treatment.MethodologyThis is a prospective, cross sectional study, include 65 women (30 with breast cancer, 35 healthy) met the study criteria. the serum VEGF-C values were measured at the beginning and after finishing the treatment.ResultsThere is no differences in age between two groups, The mean of serum VEGF-C values was higher in breast cancer patients (1122.74±853.97 U/L vs 334.55±522.6 U/L; P<0.00),. Serum VEGF-C level was significantly higher in breast cancer patients before the treatment compared with after treatment (P <0.01).Serum VEGF-C value has a good correlation with breast cancer.

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Available abstract

BackgroundBreast cancer is the second most common cancer in females. VEGF-C overexpression has been reported in breast cancer patients, and correlates with metastasis and poor prognosis. Objective: Determination the serum VEGF-C concentration in breast cancer patients, and its change after treatment.MethodologyThis is a prospective, cross sectional study, include 65 women (30 with breast cancer, 35 healthy) met the study criteria. the serum VEGF-C values were measured at the beginning and after finishing the treatment.ResultsThere is no differences in age between two groups, The mean of serum VEGF-C values was higher in breast cancer patients (1122.74±853.97 U/L vs 334.55±522.6 U/L; P<0.00),. Serum VEGF-C level was significantly higher in breast cancer patients before the treatment compared with after treatment (P <0.01).Serum VEGF-C value has a good correlation with breast cancer.

Key concepts: VEGF receptors, Vascular endothelial growth factor, Breast cancer, Vascular endothelial growth factor C, Medicine, Value (mathematics), Internal medicine, Oncology

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