2002•Nihon Naika Gakkai ZasshiOpen access

POEMS syndrome with increased vascular endothelial growth factor(VEGF).

Hirata Sintaro, Okamoto Hiroshi, Shuji Ohta, Uesato Masashi, Taniguchi Atsuo, Chihiro Terai, Hara Masako, Kamatani Naoyuki

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Abstract

症例は58歳女性,下肢脱力と全身倦怠感を主訴に受診し,多発性神経炎,肝脾腫・甲状腺機能低下症, Mタンパク,皮膚硬化を認めPOEMS症候群と診断した.肺高血圧症の合併も認めた.ステロイドパルス療法を行い症状改善,治療前vascular endothelial growth factor (VEGF)の異常高値を認めたが治療後減少した. POEMS症候群は稀な疾患であるが, VEGFの推移を追跡し疾患活動性の指標として有用であったので報告する.

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Available abstract

Key concepts: POEMS syndrome, Medicine, Vascular endothelial growth factor, VEGF receptors, Vascular endothelial growth factor C, Vascular endothelial growth factor B, Vascular endothelial growth factor A, Poetry