2020•Stem Cell ResearchOpen access

Generation of human induced pluripotent stem cell line UNIGEi003-A from skin fibroblasts of an apparently healthy male donor

Érika Cosset, Vannary Tieng, Frédérique Sloan‐Béna, Stefania Gimelli, Eric Gerstel, Karl‐Heinz Krause, Antoine Marteyn

Abstract

Dermal fibroblasts isolated from an apparently healthy 50-year-old man were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The generated iPSC line has been expanded under feeder-free conditions and displayed all hallmarks of a standard pluripotent stem cell line such as a normal karyotype, expression of pluripotent factors and differentiation capacity into the three germ layers.

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Available abstract

Key concepts: Induced pluripotent stem cell, Reprogramming, Germ layer, Biology, Cell biology, Karyotype, Sendai virus, Stem cell