CLINICAL STUDY OF THE EFFECT OF VARICOCELECTOMY ON PARAMETERS OF SEMEN ANALYSIS OF INFERTILE MEN
Anupam Kakade, Mangesh Padamwar, Dilip Gode, Chandrashekhar Mahakalkar, Ajonish Kamble, Amit Nagdive
Abstract
Anupam Kakade, Mangesh Padamwar, Dilip Gode, Chandrashekhar Mahakalkar, Ajonish Kamble, Amit Nagdive
Abstract
Background: Varicocele is the most widely seen and reversible cause of infertility to the male component. Yet varicocele's precise pathophysiology is not known till date. Our study aimed to assessing the effect of varicocele on the semen composition characteristics by examining semen before and after varicocele ligation and also assessing changes in fertility status after varicocele ligation. The goal is to compare sperm counts, motility and morphology with teratozoospermia and asthenozoospermia in patients with varicocele. (where motility and morphology of the sperm is abnormal). Methods: Over a period of 1 year 61 cases of diagnosed varicocele associated with male infertility over a 5- year period were included. All the patients underwent pre-operative and post-operative study of semen analysis with 3 to 6 months interval after varicocelectomy surgery. Results: In baseline semen analysis the median sperm concentration of 51 patients was 8 million / ml, and the median overall sperm count was 18 million patients. The rate of sperm motility forward median (A + B percent) in 51 cases was 20 percent. In 51 patients the median normal sperm morphology was 8 per cent. Compared to other modalities such as inguinal surgery and laparoscopic surgery, post-operative sperm count and motility improvement were marginally better in sub-inguinal varicocelectomy surgery when compared with the results. Conclusion: Varicocelectomy gives the production of sperm, motility, and overall morphology a statistically significant increase. Both approaches to varicocelectomy (sub-inguinal, inguinal, or laparoscopic) have shown substantial improvement in seminal parameters, with the sub-inguinal approach being successful at improving motility parameters.
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Background: Varicocele is the most widely seen and reversible cause of infertility to the male component. Yet varicocele's precise pathophysiology is not known till date. Our study aimed to assessing the effect of varicocele on the semen composition characteristics by examining semen before and after varicocele ligation and also assessing changes in fertility status after varicocele ligation. The goal is to compare sperm counts, motility and morphology with teratozoospermia and asthenozoospermia in patients with varicocele. (where motility and morphology of the sperm is abnormal). Methods: Over a period of 1 year 61 cases of diagnosed varicocele associated with male infertility over a 5- year period were included. All the patients underwent pre-operative and post-operative study of semen analysis with 3 to 6 months interval after varicocelectomy surgery. Results: In baseline semen analysis the median sperm concentration of 51 patients was 8 million / ml, and the median overall sperm count was 18 million patients. The rate of sperm motility forward median (A + B percent) in 51 cases was 20 percent. In 51 patients the median normal sperm morphology was 8 per cent. Compared to other modalities such as inguinal surgery and laparoscopic surgery, post-operative sperm count and motility improvement were marginally better in sub-inguinal varicocelectomy surgery when compared with the results. Conclusion: Varicocelectomy gives the production of sperm, motility, and overall morphology a statistically significant increase. Both approaches to varicocelectomy (sub-inguinal, inguinal, or laparoscopic) have shown substantial improvement in seminal parameters, with the sub-inguinal approach being successful at improving motility parameters.
Key concepts: Varicocele, Semen, Asthenozoospermia, Medicine, Sperm, Infertility, Semen analysis, Sperm motility