Relationship between serum high-sensitivity C-reactive protein and carotid artery plaque stability in cerebral infarction patients

Objective To explore the relationship between high-sensitivity C-reactive protein (hs-CRP) and carotid plaque stability.Methods 155 cases confirmed cerebral infarction by head CT/MRI were divided into group without plaque,plaque vulnerability group and plaque stability group.Serum levels of hs-CRP,lipids,creatinine and uric acid were measured.Results Logistic regression analysis was used to analyze the parameters of all the patients'age,serum TC,LDL-C,HDL and HDL-C,serum creatinine,hs-CRP and uric acid.Only hs-CRP level was the risk factor of carotid plaque(RR =1.301,95％ CI =1.041 ～ 1.599,P =0.010).Serum hs-CRP level in patients with vulnerable plaque was significantly higher than the group without plaque and plaque stability group.Conclusion The detection of serum hs-CRP and carotid artery ultrasound can make early diagnosis and intervention to reduce the incidence and mortality of cerebral infarction for plaque instability patients. Key words: Braiu infarction;  Carotid Stenosis