Levels of serum high sensitivity C-reactive protein and its correlation factors in acute cerebral infarction patients

Objective To investigate the levels of serum high sensitivity C-reactive protein(hs-CRP) in acute cerebral infarction patients(ACI) and the relationship between the hs-CRP levels and its correlation factors.Methods 62 patients with acute cerebral infarction were received carotid ultrasonographic examination,and then were classified into plaque group(n = 39) and non-plaque group(n =23).The serum hs-CRP levels and some other biochemical indexes were measured in 72 hrs after the onset.20 healthy people without carotid plaque were enrolled as control group.Results The level of serum hs-CRP in plaque group was higher than that of non- plaque group and control group(P 0.05),but no significant differences between non- plaque group and control group(P 0.05).The level of serum hs-CRP was positively correlated with TC(r= 0.321,P =0.011),LDL-C(r =0.341,P =0.007),HbA_(1c)(r =0.264,P =0.038),Fib(r =0.282,P =0.026),UA (r =0.284,P =0.025 ).Conclusion The level of serum hs-CRP is obviously increased in acute cerebral infarction patients with carotid plaques.There existed certain relation between the serum hs-CRP and the development of carotid plaques.