Relationship of plasma BNP monitoring and cardiac function classification in elderly patients with ST-segment elevation acute myocardial infarction

Objective To study the relationship of plasma BNP monitoring and cardiac function classification in elderly patients with ST-segment elevation acute myocardial infarction which intravenous thrombolysis of the early period. Methods 92 patients with acute myocardial infarction who got recanalization therapies by intravenous thrombolysis within 6 hours after myocardial infarction were selected.All the patients were divided into four groups by Killip classification criteria,the BNP level was compared.Comparison of plasma BNP levels in patients with different LVEF,and statistical analysis were conducted. Results With the increase of cardiac function classification,AMI in patients with BNP levels gradually increased(F= 56.144,P< 0.05),LVEF reduction in AMI serum BNP levels gradually increased,the difference was statistically significant(F= 79.234,P<0.05). Conclusion The plasma BNP levels of patients with acute myocardial infarction was higher,the heart function was lower.BNP can reflect the heart function,and can be served as an effective marker of clinical diagnosis observation of therapeutic effect,risk stratification and judgement of prognosis in patients with acute myocardial infarction. Key words: Myocardial ischemia; Natriuretic peptide,brain; Ventricular function; Aged