2010•Guoji zhongliuxue zazhiRequires access

Inhibitor of apoptosis protein XIAP and malignant tumor

Zhiqiang Chen, L. M. Song

Abstract

XIAP(X-linked inhibitor of apoptosis protein)is one of the most important members of IAPs family.It inhibits cell apoptosis mainly by inhibiting the caspases activation and interfering with other apoptotic pathway,which plays a critical role in tumor development.Recently,genetic therapy targeting on XIAP for malignant tumors has deeply developed.Research on XIAP as a malignant and prognositic indicator is ongoing. Key words: X-linked inhibitor of apoptosis protein; Apoptosis; Neoplasms

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: XIAP, Inhibitor of apoptosis, Apoptosis, Cancer research, Caspase, Inhibitor of apoptosis domain, Biology, Programmed cell death