Analysis of causes and prognosis of 113 patients with severe acute pancreatitis

Objective To better understand the causes and prognosis of severe acute pancreatitis (SAP).Methods The cause,gender,age,length of hospital stay and prognosis were retrospectively analyzed in the data of 113 hospitalized patients from January 2004 to August 2010.Results The causes of 113 patients were biliary(31.88％ ),alcoholic(42.48％ ),idiopathic(8.85％ ),hyperlipidemic( 11.5％ ) and mixed(8.31％ ).The rate of male/female was 2.65/1 ( P ＜ 0.01 ).The mean age of patients with biliary,acoholic,idiopathic,hyperlipidemic and mixed acute pancreatitis were 61.89 ± 11.32,45.73 ± 9.70,45.20 ± 10.92,53.23 ± 8.52,56.27 ± 8.53 years,.respectively ( P =0.000).The length of hospital stay of these groups were 21.11 ± 11.50,19.54 ± 16.57,16.00 ± 5.19,21.61 ±8.02,10.83 ± 9.64 days,respectively ( P =0.396).There were not significant differences about cure rate and mortality among groups( P ＞0.05 ).Conclusion The majority causes of SAP were biliary and alcoholic,and the acohol was the most cause.Biliary SAP was highest in older patients,whereas acoholic,idiopathic and hyperlipidemic SAP were highest in young patients.Although the difference was not statistically significant,the mortality of acoholic and mixed SAP were higher. Key words: Pancreatitis; Risk factors; Prognosis