Psychological factors in functional dyspepsia and its treatment

Objective To investigate the role of psychological factors in functional dyspepsia (FD) and effect of antidepressant drugs on FD. Methods To analyze the psychological status of 24 FD patients and 24 healthy people using Hamilton Depression (HAMD), Hamilton Anxiety (HAMA) and SCL90 scales. Antidepressants were used to treat FD patients for 8 weeks, 11 cases with prozac, 13 cases received seroxat. Psychological analysis was done before and after the treatment. Results There was significant difference in somatic and psychological scores in HAMA and SCL90 scores between the two groups (P0.001). The scores of FD patients improved significantly after 8 weeks treatment (P0.001). Conclusion Psychological factors play a role in FD. The patients depression or anxiety commonly occurred in these patients, and antidepressants are effective in the treatment of FD for improving both somatic and psychological symptoms.