刘海义, 梁小波, 李建民, 丛娟, 白文启, 郗彦风, 李耀平
Abstract
目的:评价力尔凡对直肠癌MMP-7表达的影响及临床意义.方法:将32例低位直肠癌患者随机分为力尔凡治疗组与对照组,治疗组在术前瘤体内注射力尔凡后接受手术治疗,对照组仅接受手术治疗,并通过免疫组化法分别检测两组MMP-7的表达.结果:MMP-7在对照组与力尔凡治疗组的表达明显高于对照组,分别为85.7%,68.7%,有显著性差异;对照组中DukesB期和C期MMP-7的表达有显著性差异.结论:术前瘤体内注射力尔凡,可明显降低直肠癌MMP-7的表达,在Dukes C期比B期更明显。
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目的:评价力尔凡对直肠癌MMP-7表达的影响及临床意义.方法:将32例低位直肠癌患者随机分为力尔凡治疗组与对照组,治疗组在术前瘤体内注射力尔凡后接受手术治疗,对照组仅接受手术治疗,并通过免疫组化法分别检测两组MMP-7的表达.结果:MMP-7在对照组与力尔凡治疗组的表达明显高于对照组,分别为85.7%,68.7%,有显著性差异;对照组中DukesB期和C期MMP-7的表达有显著性差异.结论:术前瘤体内注射力尔凡,可明显降低直肠癌MMP-7的表达,在Dukes C期比B期更明显。
Key concepts: Colorectal cancer, Matrix metalloproteinase, Expression (computer science), Medicine, Cancer, Oncology, Internal medicine, Computer science