Correlation between allergic rhinitis and bronchial asthma in children and analysis on common allergens
Liang Chen, Jun Bai
Abstract
Liang Chen, Jun Bai
Abstract
Objective To investigate the correlation between allergic rhinitis and bronchial asthma in children. Methods Fifty children with allergic rhinitis complicated with bronchial asthma who were followed up in Clinic of Foshan Women and Children’s Hospital from May 2015 to May 2017 were selected as experimental group; 50 children only with allergic rhinitis in the same period were selected as control group A; 50 children only with bronchial asthma in the same period were selected as control group B. Serum total IgE, serum allergen types and specific IgE (sIgE) were detected by allergen screening, and levels of total IgE and sIgE were compared among the three groups. Results ①The positive rate of serum sIgE in experimental group and control group B was significantly higher than that in control group A (P 0.05). Conclusions Pediatric allergic rhinitis and most bronchial asthma in children belong to IgE-mediated type I allergic reaction. The main inhaled allergens in Foshan area are mites, house dust, mold, cat hair dander and dog hair dander. Mite is the most important inhaled allergen in this area. Early prevention and treatment should be implemented in clinical for children with allergic rhinitis and bronchial asthma. Key words: Pediatric allergic rhinitis; Bronchial asthma; Correlation
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Objective To investigate the correlation between allergic rhinitis and bronchial asthma in children. Methods Fifty children with allergic rhinitis complicated with bronchial asthma who were followed up in Clinic of Foshan Women and Children’s Hospital from May 2015 to May 2017 were selected as experimental group; 50 children only with allergic rhinitis in the same period were selected as control group A; 50 children only with bronchial asthma in the same period were selected as control group B. Serum total IgE, serum allergen types and specific IgE (sIgE) were detected by allergen screening, and levels of total IgE and sIgE were compared among the three groups. Results ①The positive rate of serum sIgE in experimental group and control group B was significantly higher than that in control group A (P 0.05). Conclusions Pediatric allergic rhinitis and most bronchial asthma in children belong to IgE-mediated type I allergic reaction. The main inhaled allergens in Foshan area are mites, house dust, mold, cat hair dander and dog hair dander. Mite is the most important inhaled allergen in this area. Early prevention and treatment should be implemented in clinical for children with allergic rhinitis and bronchial asthma. Key words: Pediatric allergic rhinitis; Bronchial asthma; Correlation
Key concepts: Medicine, Asthma, Dander, Immunoglobulin E, Allergen, Immunology, House dust mite, Allergy