2008Zhonghua jianyan yixue zazhiRequires access

Strengthen the application of platelet function tests in monitoring antiplatelet drug treatment

Jianzhong Wang

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Abstract

Many platelet function tests can be used for monitoring antiplatelet drug for the prevention and treatment of thrombotic diseases.These monitoring tests may be chosen based on different antiplatelet drugs which include aspirin,clopidogrel and GP Ⅱ b/Ⅲ a antagonist.There is difference of the drug resistance which is validated by different platelet function tests,and the relation with clinical adverse events should be farther clarifled. Key words: Platelet function tests; Platelet aggregation inhibitors; Drug monitoring; Aspirin; Ticlopidine; Platelet membrane glyeoproteins

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What this paper is about

Many platelet function tests can be used for monitoring antiplatelet drug for the prevention and treatment of thrombotic diseases.These monitoring tests may be chosen based on different antiplatelet drugs which include aspirin,clopidogrel and GP Ⅱ b/Ⅲ a antagonist.There is difference of the drug resistance which is validated by different platelet function tests,and the relation with clinical adverse events should be farther clarifled. Key words: Platelet function tests; Platelet aggregation inhibitors; Drug monitoring; Aspirin; Ticlopidine; Platelet membrane glyeoproteins

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Available abstract

Many platelet function tests can be used for monitoring antiplatelet drug for the prevention and treatment of thrombotic diseases.These monitoring tests may be chosen based on different antiplatelet drugs which include aspirin,clopidogrel and GP Ⅱ b/Ⅲ a antagonist.There is difference of the drug resistance which is validated by different platelet function tests,and the relation with clinical adverse events should be farther clarifled. Key words: Platelet function tests; Platelet aggregation inhibitors; Drug monitoring; Aspirin; Ticlopidine; Platelet membrane glyeoproteins

Key concepts: Clopidogrel, Antiplatelet drug, Aspirin, Platelet, Ticlopidine, Drug, Medicine, Platelet aggregation

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