2008•Int J ImmunolRequires access
Analysis of lymphocyte immunophentypes in peripheral blood of onychomycosis patients with flow cytometry
Yu Sheng
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Abstract
Objective To evaluate the immunological competence in peripheral blood of the patients with onychomycosis. Methods The lymphocyte subpopalations and natural killer cells in the peripheral blood of 24 patients and a control group of 20 individuals were analysed by flow cytometry. Results The percentage of suppressor CD8+ lymphocytes in the patients were significantly higher than that in the normal controls (P < 0.05 ). No statistically significant difference was obtained in the percentages of CD3+ lymphocytes,CD4+ lymphocytes, CD19+ lymphocytes, CD16+, CD56+ lymphocytes. Conclusion CD8+ lymphocytes plays an importand role in mediating the cell mediated immunity in onychomycosis.
Key words:
Onychooycosis; Lymphocytes subpopulations ; Flow cytometry