栗世方, 周茂德, 扈国杰, 胡海燕
Abstract
鸟氨酸脱羧酶(ODC)是多胺合成的关键酶,ODC活性的改变可作为反映脑胶质瘤恶性程度的可靠的生物学标志;ODC基因的诱导与恶性肿瘤的发生及其浸润性密切相关,因而具备癌基因的特性.ODC抑制剂DFMO及针对ODC的抗酶蛋白(AZ)可能对脑胶质瘤有着潜在的治疗作用.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
鸟氨酸脱羧酶(ODC)是多胺合成的关键酶,ODC活性的改变可作为反映脑胶质瘤恶性程度的可靠的生物学标志;ODC基因的诱导与恶性肿瘤的发生及其浸润性密切相关,因而具备癌基因的特性.ODC抑制剂DFMO及针对ODC的抗酶蛋白(AZ)可能对脑胶质瘤有着潜在的治疗作用.
Key concepts: Ornithine decarboxylase, Gene expression, Gene, Expression (computer science), Glioma, Biology, Genetics, Computational biology