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Clinical study of change s of plasma nitric oxide and tumor necrosis factor levels in patients with conge stive heart failure

梁伟钧, 符益冰, 陈建英

Abstract

目的探讨充血性心力衰竭(CHF)患者血浆一氧化氮和肿瘤坏死因子(TNF)含量变化及其意义.方法检测68例充血性心力衰竭患者血浆一氧化氮和TNF含量 ,选择30例健康体检者作对照组.结果 CHF患者血浆一氧化氮和TNF水平明显高于对照组(P＜0.01),且心力衰竭程度越重,血浆一氧化氮与TNF水平越高.结论血浆一氧化氮和TNF增高是CHF病理生理特征之一,一氧化氮与T NF增高可作为判断心功能级别的一个重要指标.

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Key concepts: Medicine, Nitric oxide, Tumor necrosis factor α, Heart failure, Tumor necrosis factor alpha, Cardiology, Internal medicine