2019•国际医药卫生导报Requires access
Correlation between serum high-sensitivity C-reactive protein level and coronary heart disease confirmed by coronary angiography and its clinical significance
Le Chen, Tao Fan, Xiaodong Sheng, Xiaoqi Jin
Open publisher page 0 citations
Abstract
Objective
To explore the correlation between serum high-sensitivity C-reactive protein level and coronary heart disease confirmed by coronary angiography and its clinical significance.
Methods
From January, 2018 to February, 2019, 80 male patients with coronary heart disease were selected as an experimental group, including 24 patients with stable angina pectoris (SA), 31 patients with unstable angina pectoris (UA), and 25 patients with acute myocardial infarction (AMI); and 50 normal men without coronary heart disease were selected as a control group. All the patients were examined by coronary angiography. Their level of high-sensitivity C-reactive protein was detected.
Results
The serum hs-CRP level was (42.16±25.33) mg/L in the acute myocardial infarction (AMI) group, and was (9.21±11.52) mg/L in the unstable angina (UA) group; which were significantly higher than those in the stable angina (SA) group and the control group; and that of the AMI group was higher than that of the UA group; There were statistical difference (P 0.05) ]. The serum hs-CRP level increased with the severity of coronary artery stenosis, with a statistical difference (P<0.05).
Conclusion
Serum hs-CRP level is closely related to the severity of coronary artery disease in patients with coronary heart disease, increases with the severity of coronary artery disease, and has good clinical diagnostic value.
Key words:
Coronary heart disease; Serum high-sensitivity C-reactive protein; Coronary angiography; Correlation; Clinical significance