2017•国际医药卫生导报Requires access
Clinical value of liquid-based cervical cytology in HPV detection for patients with atypical squamous cells of undetermined significance
Caicai Huang, Yu Zhang, Biling Liao, Ying Xiao
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Abstract
Objective
To investigate whether high-risk human papilloma virus (HR-HPV) can be used as an indicator for management of patients with TCT results of atypical squamous cells of undetermined significance (ASCUS).
Methods
From Jan. 1, 2016 to Dec. 30, 2016, the clinical data of 583 patients with results of ASCUS in our hospital was retrospectively analyzed. The cervical lesions of HR-HPV positive patients and HR-HPV negative patients were compared.
Results
The detection rate of grade Ⅱ and above cervical intraepithelial neoplasia (CIN) was 15.7% (47/300) in HR-HPV positive group, significantly higher than 0.7% (2/283) in HR-HPV negative group. There were no statistically significant differences in HPV infection rate or high grade cervical lesion rate among different age groups.
Conclusion
The occurrence of high grade CIN is closely related to HR- HPV infection, and the HR-HPV test can be used as a main indication for administration of patients with ASCUS.
Key words:
Atypical squamous cells of undetermined significance; Cervical intraepithelial neoplasia; Biopsy; High-risk human papilloma virus