Uterine artery chemotherapy and embolization in the treatment of special site pregnancy

Objective To investigate the clinical effect of uterine artery embolization chemotherapy in the treatment of special site pregnancy .Methods 36 patients with special site pregnacy were randomly divided into the observation group and control group .The control group received uterine curettage after uterine artery embolization treatment,the observation group received bilateral uterine artery perfusion of methotrexate combined with uterine cu -rettage after embolization therapy .Time of-HCG returned to normal ,intraoperative blood loss ,hospitalization time and incidence rate of complications were compared between the two groups .Results After treatment,the time of -HCG returned to normal,intraoperative blood loss and hospitalization time in the observation group were （27.3 ±3.2）h, （120.5 ±18.3） mL,（85.6 ±8.4） h,which were significantly less than （76.4 ±8.2） h,（375.1 ±68.4） ml and （147.1 ±10.5）h in the control group （t=6.75,4.54,4.43,all P〈0.05）.The incidence rate of complication in the observation group was 16.8%,which was significantly lower than 50.1% in the control group （χ2 =4.49,P 〈0.05）.Conclusion The uterine artery chemotherapy and embolization in the treatment of special parts of pregnancy can significantly shorten the hospitalization time and time of -HCG returned to normal ,reduce the intraoperative blood loss,the clinical effect is good ,it can be used as an effective method for the treatment of special site pregnancy . Key words: Pregnancy, ectopic ;  Embolization, therapeutic ;  Chemotherapy