2013Unpublished venueRequires access

Observation on curative effect of the atorvastatin treatment for coronary heart disease after traitement interventionnelle

Yong Li

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Abstract

Objective To discuss the curative effect and safety of the atorvastatin treatment for coronary heart disease after percutaneous coronary intervention about blood fat and inflammatory factor.Methods We chose 134 patients with coronary heart disease,who accepted the percutaneous coronary intervention,and were randomly divided into two groups,67 cases in the control group were treated by the conventional therapy and atorvastatin 20 mg every day,67 cases in the observation group were treated by the conventional therapy and atorvastatin 80 mg every day,observed the blood fat,hypersensitive3 C-reactive protein (hs-CRP)and heart risk event in two groups after using medication.Resulta After 12 weeks,the level of the blood fat and the level of hs-CRP in the observation group were more excellent than those of the control group ( P<0.05).The restenosis rate of the observation group was 5.97%,which was lower than that with control group with 19.40%( P<0.05 ),the left ventricular ejection fraction of the observation group was higher than that of the control group ( P<0.05).The incidence rate of the heart ischemia event of the control group was 14.93%,the observation group was 4.48%,there were statistical significances between two groups ( P<0.05 ).There was no serious untoward effect happening in two groups.Conclusions The atorvastatin treatment for coronary heart disease after traitement interventionnelle with restenosis has preventative effect,the curative effect is excellent with the high dose,good safety,and no serious untoward effect. Key words: Coronary heart disease; Percutaneous coronary intervention; Atorvastatin

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Objective To discuss the curative effect and safety of the atorvastatin treatment for coronary heart disease after percutaneous coronary intervention about blood fat and inflammatory factor.Methods We chose 134 patients with coronary heart disease,who accepted the percutaneous coronary intervention,and were randomly divided into two groups,67 cases in the control group were treated by the conventional therapy and atorvastatin 20 mg every day,67 cases in the observation group were treated by the conventional therapy and atorvastatin 80 mg every day,observed the blood fat,hypersensitive3 C-reactive protein (hs-CRP)and heart risk event in two groups after using medication.Resulta After 12 weeks,the level of the blood fat and the level of hs-CRP in the observation group were more excellent than those of the control group ( P<0.05).The restenosis rate of the observation group was 5.97%,which was lower than that with control group with 19.40%( P<0.05 ),the left ventricular ejection fraction of the observation group was higher than that of the control group ( P<0.05).The incidence rate of the heart ischemia event of the control group was 14.93%,the observation group was 4.48%,there were statistical significances between two groups ( P<0.05 ).There was no serious untoward effect happening in two groups.Conclusions The atorvastatin treatment for coronary heart disease after traitement interventionnelle with restenosis has preventative effect,the curative effect is excellent with the high dose,good safety,and no serious untoward effect. Key words: Coronary heart disease; Percutaneous coronary intervention; Atorvastatin

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Available abstract

Objective To discuss the curative effect and safety of the atorvastatin treatment for coronary heart disease after percutaneous coronary intervention about blood fat and inflammatory factor.Methods We chose 134 patients with coronary heart disease,who accepted the percutaneous coronary intervention,and were randomly divided into two groups,67 cases in the control group were treated by the conventional therapy and atorvastatin 20 mg every day,67 cases in the observation group were treated by the conventional therapy and atorvastatin 80 mg every day,observed the blood fat,hypersensitive3 C-reactive protein (hs-CRP)and heart risk event in two groups after using medication.Resulta After 12 weeks,the level of the blood fat and the level of hs-CRP in the observation group were more excellent than those of the control group ( P<0.05).The restenosis rate of the observation group was 5.97%,which was lower than that with control group with 19.40%( P<0.05 ),the left ventricular ejection fraction of the observation group was higher than that of the control group ( P<0.05).The incidence rate of the heart ischemia event of the control group was 14.93%,the observation group was 4.48%,there were statistical significances between two groups ( P<0.05 ).There was no serious untoward effect happening in two groups.Conclusions The atorvastatin treatment for coronary heart disease after traitement interventionnelle with restenosis has preventative effect,the curative effect is excellent with the high dose,good safety,and no serious untoward effect. Key words: Coronary heart disease; Percutaneous coronary intervention; Atorvastatin

Key concepts: Medicine, Atorvastatin, Restenosis, Coronary heart disease, Internal medicine, Cardiology, Ejection fraction, Percutaneous coronary intervention

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