2011•Guoji shuxue ji xueyexue zazhiRequires access
Study on Database of RhD-Negative Blood Group in Umbilical Cord Blood
Qian Li, Le-Jing Sun, Ying Jun Du, Lan-ting Liu, Jian Liu, WU Wen-ji, Lugui Qiu
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Abstract
Objective A RhD-negative blood group database was established in Tianjin CBB to explore the distribution of RhD-negative blood group.Methods 154 882 cases of neonatal health UCB samples as the research object were collected between October 2001 and August 2011 of Tianjin CBB.The ABO blood group antigen and RhD antigen were detected by standard tube agglutination test.RhD-negative was confirmed by indirect antiglobulin test.Results 581(0.37％)RhD-negative cases were detected in total of 154 882 UCB samples,including type A 137 cases(23.58％),type B 191cases(32.87％),type O 195 cases(33.56％)and type AB 58 cases(9.98％),mainly 51.98％ in males and 48.02％ in females.The major antigen phenotypes of RhD-negative blood type were ccdee and Ccdee phenotype(81.67％).Conclusion With RhD-negative blood group database of neonate umbilical cord blood established,the reference data of scientific blood use,clinical prophylaxis and therapy would be provided.
Key words:
umbilical cord blood; cord blood bank; RhD blood-group; database