2007•International journal of pediatricsRequires access

Progress of Gene Polymorphism in Respiratory Syncytial Virus Bronchiolitis

黄志英, 韩晗, 董琳

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Abstract

呼吸道合胞病毒(RSV)是婴幼儿呼吸道感染最常见的病原.感染RSV以后多数患儿仅表现为上呼吸道感染,而少数则出现需住院治疗的严重毛细支气管炎(毛支)和肺炎.导致这种病情差异的原因尚不清楚,随着对其遗传学研究的不断深入,通过对RSV毛支患儿基因型的分析,发现白细胞介素-8,4,10和表面活性蛋白等均存在基因多态性,且与RSV毛支的疾病易感性、病情严重程度等相关。

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What this paper is about

呼吸道合胞病毒(RSV)是婴幼儿呼吸道感染最常见的病原.感染RSV以后多数患儿仅表现为上呼吸道感染,而少数则出现需住院治疗的严重毛细支气管炎(毛支)和肺炎.导致这种病情差异的原因尚不清楚,随着对其遗传学研究的不断深入,通过对RSV毛支患儿基因型的分析,发现白细胞介素-8,4,10和表面活性蛋白等均存在基因多态性,且与RSV毛支的疾病易感性、病情严重程度等相关。

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Available abstract

呼吸道合胞病毒(RSV)是婴幼儿呼吸道感染最常见的病原.感染RSV以后多数患儿仅表现为上呼吸道感染,而少数则出现需住院治疗的严重毛细支气管炎(毛支)和肺炎.导致这种病情差异的原因尚不清楚,随着对其遗传学研究的不断深入,通过对RSV毛支患儿基因型的分析,发现白细胞介素-8,4,10和表面活性蛋白等均存在基因多态性,且与RSV毛支的疾病易感性、病情严重程度等相关。

Key concepts: Medicine, Bronchiolitis, Respiratory system, Virology, Virus, Polymorphism (computer science), Gene, Immunology

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