Clinical study of the detection of respiratory syncytial virus in the respiratory tract in fection of children
陶明方, 周馥英, 陆耀英, 叶惠琴
Abstract
陶明方, 周馥英, 陆耀英, 叶惠琴
Abstract
目的探讨小儿呼吸道合胞病毒(RSV)感染和临床特征.方法用生物素-链霉亲和素-过氧化物酶法检测113例急性下呼吸道感染患儿的鼻咽部脱落细胞中RSV抗原,并对47例RSV阳性病例的临床特征进行分析.结果 RSV抗原阳性率为41.6%,临床典型和可疑病例抗原检出率分别为47.9%和44.9%,临床不典型者阳性率12.5%,x2=7.9 P<0.05.下呼吸道感染的喘息型组RSV阳性率51.9%,非喘息型组RSV阳性率32.2%,x2=4.48,P<0.05.47例RSV阳性中3 a内喘息率67.6%(25/37例),明显高于3 a以上组30.0%(3/10例),x2=5.17 P<0.05.不同年龄、病期、临床诊断组RSV抗原阳性率差异无统计学意义.结论小儿下呼吸道感染约40%可有RSV引起,各年龄组小儿均对RSV易感,在喘息型下呼吸道感染中RSV所致多见,年龄越小发生喘息越多.
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目的探讨小儿呼吸道合胞病毒(RSV)感染和临床特征.方法用生物素-链霉亲和素-过氧化物酶法检测113例急性下呼吸道感染患儿的鼻咽部脱落细胞中RSV抗原,并对47例RSV阳性病例的临床特征进行分析.结果 RSV抗原阳性率为41.6%,临床典型和可疑病例抗原检出率分别为47.9%和44.9%,临床不典型者阳性率12.5%,x2=7.9 P<0.05.下呼吸道感染的喘息型组RSV阳性率51.9%,非喘息型组RSV阳性率32.2%,x2=4.48,P<0.05.47例RSV阳性中3 a内喘息率67.6%(25/37例),明显高于3 a以上组30.0%(3/10例),x2=5.17 P<0.05.不同年龄、病期、临床诊断组RSV抗原阳性率差异无统计学意义.结论小儿下呼吸道感染约40%可有RSV引起,各年龄组小儿均对RSV易感,在喘息型下呼吸道感染中RSV所致多见,年龄越小发生喘息越多.
Key concepts: Respiratory system, Medicine, Respiratory tract, Virus, Virology, Internal medicine