2017•国际医药卫生导报Requires access
The curative effect analysis of Shenmai injection in the treatment of patients with septic shock and its effect on cellular immune function
Wenming Zhang
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Abstract
Objective
To investigate the clinical efficacy of Shenmai injection in the treatment of patients with septic shock and its effect on cellular immune function.
Methods
82 cases of patients with septic shock were randomly divided into experimental group (n=41) and control group (n=41). The control group was given western medical therapy, and the experimental group was treated with Shenmai injection on the basis of the treatment in the control group. Both groups were treated for 7 d. Made a comparison of clinical efficacy, changes of blood lactate, proealcitonin(PCT), and cellar immune function before and 7 d after treatment in both groups.
Results
The improvement rate in the experimental group was significantly higher than that in the control group (70.73% vs.46.34%), with statistically significant difference (P 0.05); compared with before treatment, the levels of CD3+, CD4+, CD4+/CD8+ in the experimental group after treatment significantly increased, with statistically significant differences (P<0.05); the levels of CD3+, CD4+, CD4+/CD8+ after treatment in the experimental group were significantly higher than those in the control group, with statistically significant differences (P<0.05).
Conclusion
Shenmai injection in the treatment of patients with septic shock has striking clinical effect, which can improve cellular immune function of patients obviously.
Key words:
Septic shock; Shenmai injection; Clinical efficacy; Cellular immune function