Investigation on the Resistance of Shenmai Injection Against Toxicity of Tumor Chemotherapy and Its Immune Regulation

Objective To investigate the resistance of Shenmai injection against toxicity of chemotherapy for tumor and its immune regulation function.Methods A total of 258 tumor patients were randomly divided as trial group and control group.The patients in control group received routine chemotherapy and symptomatic treatment; while those in trial group received intravenous Shenmai injection,60 ml in 5% glucose solution 500 ml,once a day,based on the treatment for control group.All patients in the two groups were given tests of liver function,blood routine,immunoglobulin and T cell subsets before and after treatment.Results After treatment between the two groups,a significant difference in (1) alanine transaminase(ALT) and aspartate aminotransferase(AST) was found( P 0.01);(2)leukocyte and blood platelet counts( P 0.01);(3)IgG,IgA,and IgM contents( P 0.01);(4)CD+_4,CD+_8,and CD+_4/CD+_8( P 0.01).Conclusion Shenmai injection is of the effects of checking the toxicity of chemical drugs,improving the liver functions,raising the blood picture,and strengthening the immunity.