Value of laparoscopy in the diagnosis of female patients with unexplained ascites and elevated serum tumor marker level

Objective To assess the value of laparoscopic exploration in diagnosing female patients with unknown origin ascites and high serum tumor marker level.Methods The clinical datas of 30 female patients with unknown origin ascites underwent diagnostic laparoscopic abdominal exploration and biopsy from Jan.2007 to Oct.2010 were retrospectively analyzed.Results Among the 30 cases,29 cases were identified by laparoscopic abdominal exploration and biopsy.The total definite diagnostic rate was 96.7％.One case was negative.All pelvic tuberculosis with ascites underwent antituberculosis therapy.Three cases gave up treatment.Twelve malignant tumors were treated by intraperitoneal chemotherapy.Clinical complete regression of ascites was achieved,and the tumor marker level decreased to normal level in 9 patients.Conclusions Laparoscopic technique with high definite diagnostic rate,less wound,recovered quick and time - saving is gradually becoming a useful method for diagnosing female patients with unknown origin ascites and high serum tumor marker level. Key words: Laparoscopy; Ascites; Tumor marker; Female