2017•Zhonghua shenjing waike zazhiRequires access
Individualized surgical scheme for secondary epilepsy in children with temporal lobe gangliogliomas
Jiuluan Lin, Wei Chen, Zhaohui Sun, Bingqing Zhang, Haixiang Wang, Wenjing Zhou
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Abstract
Objective
To discuss individualized surgical scheme for secondary epilepsy in children with temporal lobe gangliogliomas.
Methods
A total of 14 children with temporal lobe gangliogliomas received surgical treatment for refractory epilepsy at Epilepsy Center, Yuquan Hospital, Tsinghua University from September 2008 to September 2016 and were enrolled into this study. Their clinical demonstrations, imaging features, electroencephalography (EEG) characteristics and surgical procedures were retrospectively analyzed.
Results
Among those 14 patients, 5 cases received standard anterior temporal lobectomy with amygdalohippocampectomy, 2 cases underwent selective amygdalohippocampectomy, and the other 7 cases received selective resection of temporal structures. All patients were followed up for 1-8 years which demonstrated the outcomes of Engle grade Ⅰ in 12 cases and Engle grade Ⅱ in 2 cases. Gangliogliomas (WHO grade Ⅰ) were confirmed in all cases by pathological examination.
Conclusions
For secondary epilepsy in children with temporal lobe gangliogliomas, good outcomes could be achieved by following individualized surgical scheme based on the tumor locations, symptoms and EEG results.
Key words:
Ganglioglioma; Epilepsy; Temporal lobe; Neurosurgical procedures; Child