Effects of hyperbaric oxygen on the expression of serum soluble intercellular adhesion molecule-1 in elderly patients with cerebral infarction
严丽荣, 朱秋亚, 张春玉, 华琴, 周宏图
Abstract
严丽荣, 朱秋亚, 张春玉, 华琴, 周宏图
Abstract
目的 探讨老年脑梗死患者高压氧(HBO)治疗前后体内可溶性细胞间粘附分子-1(sICAM-1)表达水平的变化及其与疾病变化相关性.方法选择老年脑梗死患者及老年健康体检者各20例,通过ELISA法分别检测其血清sICAM-1水平并进行组间比较.结果脑梗死组sICAM-1值高于正常对照组,其组间差别具有统计学意义(P<0.01).HBO治疗后脑梗死组sICAM-1水平显著降低(P<0.01),与正常对照组比较差别无统计学意义(P>0.05).结论 HBO可明显抑制老年脑梗死患者体内sICAM-1的表达。
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目的 探讨老年脑梗死患者高压氧(HBO)治疗前后体内可溶性细胞间粘附分子-1(sICAM-1)表达水平的变化及其与疾病变化相关性.方法选择老年脑梗死患者及老年健康体检者各20例,通过ELISA法分别检测其血清sICAM-1水平并进行组间比较.结果脑梗死组sICAM-1值高于正常对照组,其组间差别具有统计学意义(P<0.01).HBO治疗后脑梗死组sICAM-1水平显著降低(P<0.01),与正常对照组比较差别无统计学意义(P>0.05).结论 HBO可明显抑制老年脑梗死患者体内sICAM-1的表达。
Key concepts: Intracellular, Oxygen, Cell adhesion molecule, Adhesion, Intercellular Adhesion Molecule-1, Cerebral infarction, Internal medicine, Medicine