2005肿瘤研究与临床Requires access

Clinical significance of serum sICAM-1 levels in patients with colorectal carcinoma

于哈娜, 石红梅, 张英兰

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Abstract

目的 研究可溶性细胞间黏附分子1(sICAM-1)与大肠癌转移的关系.方法用ELISA双抗体夹心法测定大肠癌患者50例及对照组30例血清sICAM-1水平.结果大肠癌组血清sICAM-1水平高于对照组(P<0.05),无转移大肠癌组与对照组相比差异无统计学意义(P>0.05),有转移的大肠癌组高于对照组(P<0.01),也高于无转移大肠癌组(P<0.01),低分化癌组高于高分化癌组(P<0.05).结论sICAM-1水平增高与大肠癌的侵袭转移有关。

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目的 研究可溶性细胞间黏附分子1(sICAM-1)与大肠癌转移的关系.方法用ELISA双抗体夹心法测定大肠癌患者50例及对照组30例血清sICAM-1水平.结果大肠癌组血清sICAM-1水平高于对照组(P<0.05),无转移大肠癌组与对照组相比差异无统计学意义(P>0.05),有转移的大肠癌组高于对照组(P<0.01),也高于无转移大肠癌组(P<0.01),低分化癌组高于高分化癌组(P<0.05).结论sICAM-1水平增高与大肠癌的侵袭转移有关。

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Available abstract

目的 研究可溶性细胞间黏附分子1(sICAM-1)与大肠癌转移的关系.方法用ELISA双抗体夹心法测定大肠癌患者50例及对照组30例血清sICAM-1水平.结果大肠癌组血清sICAM-1水平高于对照组(P<0.05),无转移大肠癌组与对照组相比差异无统计学意义(P>0.05),有转移的大肠癌组高于对照组(P<0.01),也高于无转移大肠癌组(P<0.01),低分化癌组高于高分化癌组(P<0.05).结论sICAM-1水平增高与大肠癌的侵袭转移有关。

Key concepts: Colorectal cancer, Medicine, Internal medicine, Clinical significance, Carcinoma, Oncology, Gastroenterology, Cancer

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