Clinical observation of qiweiqingyan aerosol combined with ribavirin in the treatment of hand-foot-mouth disease

Objective To analyze the therapeutic effect of qiweiqingyan aerosol combined with ribavirin in the treatment of herpetic angina of children hand-foot-mouth disease, and to compare the clinical effects with simple use of ribavirin. Methods 160 children with hand foot and mouth disease were divided into two groups by random number table.They were the observation group(80 cases)and control group(80 cases), respectively. Two groups were both given ribavirin aerosol in the treatment, the observation group were added with qiweiqingyan aerosol agent to carry out treatment, then the clinical curative effects of the observation group and control group were copared. Results In the observation group,the total effective rate was 96.25%,and the total effective rate of the control group was 85.00%, the difference between the two groups had statistical significance(χ2=5.959,P<0.05). Marked effective rate of the observation group was 86.25%. In the control group,the significant efficiency was 37.50%. The difference between the two groups had statistical significance (χ2=40.300,P<0.05).Defervescence time and bleb disappear time were shorter in the observation group compared to the control group, the difference between the two groups was statistically significant(t=47.880,8.063,5.100, all P<0.05). The adverse reactions in the observation group were significantly lower than those in the control group(χ2=9.608,P<0.05),after statistical analysis. Conclusion Using qiweiqingyan aerosol combined with ribavirin in the treatment of children hand foot and mouth herpangina, can significantly shorten the time of treatment, reduce adverse reactions and improve the cure rate. Key words: Qiweqingyan aerosol; Ribavirin aerosol; Hand-foot-mouth disease