2010Zhongguo xiaoer jijiu yixueRequires access

Research progress in mechanism of sepsis-induced cardiac dysfunction

Shuai Shuai, Qiyi Zeng

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Abstract

Myocardial dysfunction is a well-recognized manifestation of multiple organ dysfunction in sepsis.Although the underlying mechanisms of myocardial dysfunction during sepsis have been studied for more than 5 decades,the detailed pathophysiology of sepsis-induced myocardial dysfunction still remains unclear.The underlying mechanisms of myocardial dysfunction include mitochondrial dysfunction,circulating myocardial depressant factor,impaired calcium balance and etc. Key words: Sepsis; Cardiac dysfunction; Mechanism

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What this paper is about

Myocardial dysfunction is a well-recognized manifestation of multiple organ dysfunction in sepsis.Although the underlying mechanisms of myocardial dysfunction during sepsis have been studied for more than 5 decades,the detailed pathophysiology of sepsis-induced myocardial dysfunction still remains unclear.The underlying mechanisms of myocardial dysfunction include mitochondrial dysfunction,circulating myocardial depressant factor,impaired calcium balance and etc. Key words: Sepsis; Cardiac dysfunction; Mechanism

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Available abstract

Myocardial dysfunction is a well-recognized manifestation of multiple organ dysfunction in sepsis.Although the underlying mechanisms of myocardial dysfunction during sepsis have been studied for more than 5 decades,the detailed pathophysiology of sepsis-induced myocardial dysfunction still remains unclear.The underlying mechanisms of myocardial dysfunction include mitochondrial dysfunction,circulating myocardial depressant factor,impaired calcium balance and etc. Key words: Sepsis; Cardiac dysfunction; Mechanism

Key concepts: Medicine, Cardiac dysfunction, Sepsis, Organ dysfunction, Mechanism (biology), Pathophysiology, Immune Dysfunction, Cardiology

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