Clinical treatment of the preterm premature rupture of membranes

Objective To investigate the reason of the preterm premature rupture of membranes (PPROM),the clinical treatment in different gestational age,the influence to the mode of delivery and the perinatal infant.Methods The clinical data of 206 patients with PPROM who labored in our hospital from January 2007 to December 2010 were retrospectively analyzed,looking for causes,compare the outcome of pregnant and the mode of delivery among different gestational age.Results In the proportions of the relevant factors of PPROM abortion history was the highest (35.9％),followed by reproductive tract infections (22.8％).In the 206 patients,the cesarean section rate of the 32-34 +6 weeks of pregnant was significantly higher than the 28-31 +6 weeks and the 35-36 +6 weeks (P ＜ O.05),while there was no significant difference between the 28-31 +6 weeks and the 35-36+6 weeks pregnant (P ＞ 0.05).The outcome of pregnant was no significant difference between the 28-31 +6 weeks and the 32-34 +6 weeks (P ＞0.05),but when they compared with 35-36 +6 weeks,the difference was significant (P ＜ 0.05).Conclusions Abortion history,infection is the main reason of PPROM,cesarean section is not the best mode of delivery to reduce perinatal adverse outcomes,perinatal outcome is closely related with gestational age. Key words: Preterm premature rupture of membranes ;  Relevant factors ;  Mode of delivery; Pregnancy outcome