2020•Zhonghua heyixue yu fenzi yingxiang zazhiRequires access

Application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors

Guanyun Wang, Peng Yu, Jing Ning, Baixuan Xu

Abstract

Prostate specific membrane antigen (PSMA) is a hot topic in molecular imaging research of prostate cancer. However, non-prostate related PSMA can also be expressed in physiological tissues and different benign and malignant diseases, especially in tumor-associated endovascular endothelial cells. Related clinical studies have demonstrated the staging potential of PSMA ligands PET imaging in non-prostate tumors. This article summarizes the application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors. Key words: Prostate-specific membrane antigen; Positron-emission tomography; Trends

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Key concepts: Glutamate carboxypeptidase II, Prostate cancer, Prostate, Positron emission tomography, Medicine, Molecular imaging, Pet imaging, Cancer research