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Treatment of rheumatoid arthrictis by combined use of drugs for ten years

张宗禄, 王占元, 郑永新, 郭春霞, 高兰香

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Abstract

目的探讨类风湿关节炎远期治疗方案的选择.方法用甲氨喋呤(MTX)+柳氮磺胺吡啶(SASP)联合用药治疗早、中期RA54例,用药初期采用综合疗法,待病情基本稳定后,MTX每周10 mg,静点或口服;SASP 0.5 mg,每6h一次口服,并同时服用酵母片保护胃肠功能.观察期每半年复查肝、肾功能、血尿常规一次,每年拍一次双腕手X线片,与原片对照,同时观察副作用.结果显效27例,好转19例,总有效率83.3%,未见明显副作用.结论 MTX+SASP联合用药方案,搭配合理,疗效满意,值得进一步探讨.

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What this paper is about

目的探讨类风湿关节炎远期治疗方案的选择.方法用甲氨喋呤(MTX)+柳氮磺胺吡啶(SASP)联合用药治疗早、中期RA54例,用药初期采用综合疗法,待病情基本稳定后,MTX每周10 mg,静点或口服;SASP 0.5 mg,每6h一次口服,并同时服用酵母片保护胃肠功能.观察期每半年复查肝、肾功能、血尿常规一次,每年拍一次双腕手X线片,与原片对照,同时观察副作用.结果显效27例,好转19例,总有效率83.3%,未见明显副作用.结论 MTX+SASP联合用药方案,搭配合理,疗效满意,值得进一步探讨.

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Available abstract

目的探讨类风湿关节炎远期治疗方案的选择.方法用甲氨喋呤(MTX)+柳氮磺胺吡啶(SASP)联合用药治疗早、中期RA54例,用药初期采用综合疗法,待病情基本稳定后,MTX每周10 mg,静点或口服;SASP 0.5 mg,每6h一次口服,并同时服用酵母片保护胃肠功能.观察期每半年复查肝、肾功能、血尿常规一次,每年拍一次双腕手X线片,与原片对照,同时观察副作用.结果显效27例,好转19例,总有效率83.3%,未见明显副作用.结论 MTX+SASP联合用药方案,搭配合理,疗效满意,值得进一步探讨.

Key concepts: Medicine

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