ScholarLens Back to search
2012•Central Plains Medical JournalRequires access

Effect of alprostadil on the S100B and MMP - 9 in serum of patients with acute cerebral infarction

Ming-jun Yang

Open publisher page 0 citations

Abstract

Objective To study the the effect of alprostadil on the S100B and MMP - 9 in serum of patients with acute cerebral infarction.Methods Sixty patients were randomly divided into two groups,the control group( n =30) and the treatment group( n =30).The control group was given routine treatment,the treatment group was given alprostadil beside routine treatment.Alprostadil for 14 days.The S100B and MMP -9 in serum were tested before and after treatment.Results The S100B and MMP9 in control group was (0.71 ± 0.27 ) μg/L and ( 281 ± 95 ) μg/L.The S 100B and M MP - 9 in treatment group was (0.46 ±0.22) μg/L and (206 ±74) μg/L.After treatment,the level of s100B and MMP9 expression decreased than that before treatment,and the effect in treatment group was better than that in control group.Conclusions Alprostadil could decrease the S100B and MMP -9 in acute cerebral infarction,which was worth promotion. Key words: Cerebral infarction; Alprostadil; S100B; MMP - 9

About this research paper

What this paper is about

Objective To study the the effect of alprostadil on the S100B and MMP - 9 in serum of patients with acute cerebral infarction.Methods Sixty patients were randomly divided into two groups,the control group( n =30) and the treatment group( n =30).The control group was given routine treatment,the treatment group was given alprostadil beside routine treatment.Alprostadil for 14 days.The S100B and MMP -9 in serum were tested before and after treatment.Results The S100B and MMP9 in control group was (0.71 ± 0.27 ) μg/L and ( 281 ± 95 ) μg/L.The S 100B and M MP - 9 in treatment group was (0.46 ±0.22) μg/L and (206 ±74) μg/L.After treatment,the level of s100B and MMP9 expression decreased than that before treatment,and the effect in treatment group was better than that in control group.Conclusions Alprostadil could decrease the S100B and MMP -9 in acute cerebral infarction,which was worth promotion. Key words: Cerebral infarction; Alprostadil; S100B; MMP - 9

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To study the the effect of alprostadil on the S100B and MMP - 9 in serum of patients with acute cerebral infarction.Methods Sixty patients were randomly divided into two groups,the control group( n =30) and the treatment group( n =30).The control group was given routine treatment,the treatment group was given alprostadil beside routine treatment.Alprostadil for 14 days.The S100B and MMP -9 in serum were tested before and after treatment.Results The S100B and MMP9 in control group was (0.71 ± 0.27 ) μg/L and ( 281 ± 95 ) μg/L.The S 100B and M MP - 9 in treatment group was (0.46 ±0.22) μg/L and (206 ±74) μg/L.After treatment,the level of s100B and MMP9 expression decreased than that before treatment,and the effect in treatment group was better than that in control group.Conclusions Alprostadil could decrease the S100B and MMP -9 in acute cerebral infarction,which was worth promotion. Key words: Cerebral infarction; Alprostadil; S100B; MMP - 9

Key concepts: Medicine, Cerebral infarction, Matrix metalloproteinase, Anesthesia, MMP9, Conventional treatment, Serum concentration, Gastroenterology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effect of alprostadil on the S100B and MMP - 9 in serum of patients with acute cerebral infarction — Research Paper | ScholarLens