2016•药物不良反应杂志Requires access
Fever and rash due to fat-soluble vitamins (II) in a child
Qiaohuan Tian, Lifang Chen, Zhanquan Lin, Jian‐Xin Zhu, Jihong Zhao, Liping Ma
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Abstract
A 9-year-old girl received intravenous infusions of cefuroxime 1.5 g twice daily, fat-soluble vitamins (Ⅱ) 1 bottle once daily and water-soluble vitamin 10 ml once daily after resection of teratoma. Mild chest tightness and irritability appeared after the first infusion of fat-soluble vitamin and water-soluble vitamin. One to three hours after each infusion, her body temperature significantly increased. On day 4, erythematous spotted and patchy maculopapular rashes occurred on her face, ear, trunk, and gradually extended developed to the limbs, hand and foot. Fat-soluble vitamins (Ⅱ) was stopped, and water-soluble vitamins were continued to use. The patient′ body temperature returned to normal and the rash gradually reduced after 12 hours. On the following day, the rash disappeared.
Key words:
Medication errors; Fever; Drug eruptions; Fat-soluble vitamins (Ⅱ)