2010•Chinese Journal of Drug Application and MonitoringRequires access

One case report of anaphylactic shock induced by fat-soluble vitamin for injection (II)

Bai Qin

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Abstract

A 64-year-old male patient with prostate hyperplasia accompanied by acute urinary retention received fat-soluble vitamin for injection (Ⅱ) dissolved in 500 mL of 5% glucose injection after plasma kinetic transurethral resection of prostate. One minute later, the patient felt discomfort suddenly, and showed dizziness, somnolence, weak radial artery pulse, cold clammy limbs, skin flush with pruritus. So fat-soluble vitamin for injection (Ⅱ) was discontinued immediately. After 2-3 minutes, he appeared unconsciousness, with blood pressure of 60/40 mmHg and heart rate of 50 beats per minute. It was diagnosed as anaphylactic shock. Receiving antianaphylaxis and symptomatic treatment for one and a half hours, the patient recovered consciousness, and anaphylactic symptoms of skin disappeared.

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What this paper is about

A 64-year-old male patient with prostate hyperplasia accompanied by acute urinary retention received fat-soluble vitamin for injection (Ⅱ) dissolved in 500 mL of 5% glucose injection after plasma kinetic transurethral resection of prostate. One minute later, the patient felt discomfort suddenly, and showed dizziness, somnolence, weak radial artery pulse, cold clammy limbs, skin flush with pruritus. So fat-soluble vitamin for injection (Ⅱ) was discontinued immediately. After 2-3 minutes, he appeared unconsciousness, with blood pressure of 60/40 mmHg and heart rate of 50 beats per minute. It was diagnosed as anaphylactic shock. Receiving antianaphylaxis and symptomatic treatment for one and a half hours, the patient recovered consciousness, and anaphylactic symptoms of skin disappeared.

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Available abstract

A 64-year-old male patient with prostate hyperplasia accompanied by acute urinary retention received fat-soluble vitamin for injection (Ⅱ) dissolved in 500 mL of 5% glucose injection after plasma kinetic transurethral resection of prostate. One minute later, the patient felt discomfort suddenly, and showed dizziness, somnolence, weak radial artery pulse, cold clammy limbs, skin flush with pruritus. So fat-soluble vitamin for injection (Ⅱ) was discontinued immediately. After 2-3 minutes, he appeared unconsciousness, with blood pressure of 60/40 mmHg and heart rate of 50 beats per minute. It was diagnosed as anaphylactic shock. Receiving antianaphylaxis and symptomatic treatment for one and a half hours, the patient recovered consciousness, and anaphylactic symptoms of skin disappeared.

Key concepts: Medicine, Anesthesia, Blood pressure, Anaphylactic shock, Unconsciousness, Heart rate, Shock (circulatory), Vitamin

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