Clinical observation and nursing for the patients with acute pulmonary embolism treated with thrombolytic and anticoagulant

Objective To observe the clinical efficacy of thrombolytic and anticoagulant treatment in patients with acute pulmonary embolism ( APE),and to explore the care points before treatment,in treatment and after treatment.Methods A total of 32 patients with APE were given intravenous thrombolysis with urokinase and low molecular weight heparin and warfarin anticoagulation therapy.At the same time,monitoring and nursing were strengthened. The clinical efficacy and blood gas analysis before and after treatment were observed.Results Cure 19 patients (59.38％ ),improving 12 cases (37.50％),death 1 cases (3.12％),and the total effective rate was 96.88％.After thrombolysis and anticoagulant therapy,PaO2 by (68.1 ± 6.7) mmHg rose to (81.6 ± 6.3 ) mmHg,and PaCO2 by (57.1 ± 4.9 ) mmHg fell to ( 48.5 ± 5.0 ) mmHg,there was significant difference between before and after treatment ( P ＜ 0.01 )Conclusions Early diagnosis of APE,timely thrombolysis anticoagulant therapy,together with meticulous care can reduce mortality. Key words: Acute pulmonary embolism;  Thrombolytic;  Anticoagulant;  Nursing