Diagnostic value of transvaginal ultrasonography in intrauterine lesions

Objective To evaluate the value of transvaginal two-dimensional ultrasound(2D-TVS) and transvaginal three-dimensional ultrasound(3D-TVS) in the diagnosis of intrauterine lesions with abnormal uterine bleeding. Methods Intrauterine lesions for 171 patients underwent 2D-TVS followed by 3D-TVS in the same session. Within 10 days of the sonographic session, each patient underwent pathologic histology examination after hysteroscopy examination or surgery therapy, which was considered the reference standard.For each of the two imaging methods, sensitivity, specificity, and accuracy were calculated. Results The results of 2D-TVS and 3D-TVS had good agreement with pathological results in endometrial hyperplasia, endometrial polyps, uterus submucous myoma and endometrial cancer. For 2D-TVS, sensitivity was 84.5%, 71.4%, 86.8%, 66.7%, and specificity was 86.7%, 90.7%, 97.0%, 98.7%, respectively; For 3D-TVS, sensitivity was 91.4%, 87.3%, 92.1%, 83.3%, and specificity was 93.8%, 96.3%, 97.7%, 98.7%, respectively.The diagnose accordance rate of the 3D-TVS for intrauterine lesions was statistically higher than that of the 2D-TVS (89.5% vs 78.9%, P<0.05). Conclusions The sensitivity and diagnose accordance rate of 3D-TVS was higher than that by 2D-TVS, 3D-TVS plays an important role in the diagnosis and differential diagnosis of intrauterine lesions. Key words: Endosonography; Uterine diseases; Uterine hemorrhage