The reliability analysis of intravascular ultrasound and quantitative coronary analysis in evaluation of coronary intermediate lesion

Objective To compare the reliability of intravascular ultrasound (IVUS) and quantitative coronary analysis (QCA) used in coronary intermediate lesion. Methods 90 patients diagnosed as coronary intermediate lesion by coronary angiography were divided into QCA group(n=43) and IVUS group(n=47) according to a random number table method.The QCA group received conventional coronary angiography, while the IVUS group were given intravascular ultrasound.Minimum lumen area, diameter stenosis rate, reference vessel diameter and minimum lumen diameter of the two groups and the correlation between the two methods were compared and analyzed.The treatment plan was made according to the results, and appropriate drug intervention was administered after the treatment.The cardiovascular events in 3, 6, 9 and 12 months of the two group were also compared. Results The diameter stenosis rate of the QCA group and lumen area stenosis rate in IVUS group showed no correlation (P=0.351), and the minimum lumen area of IVUS group was (4.6±0.68)mm2.The IVUS group were analyzed by both IVUS and QCA methods.The reference vessel diameter of the two groups was positively correlated[(3.16±0.22)mm vs.(3.29±0.18)mm, r=0.627, P=0.031], and the minimal lumen diameter of the two groups was also positively associated[(2.01±0.16)mm vs.(2.03±0.19)mm, r=0.782, P=0.019]. After 1-year follow-up, the incidence rate of cardiovascular event of the QCA group was significantly higher than that of the IVUS group (χ2=4.126, P=0.033). Kaplan-Meier analysis showed that the incidence rate of cardiovascular events in the IVUS group was significantly reduced(Log-rank χ2=4.979, P=0.026). Conclusion The application of IVUS is more comprehensive in qualitative and quantitative analysis of the characteristics of the lesion, and can provide more accurate reference for reasonable treatment plan. Key words: Endosonography; Coronary angiography