The effect of accommodation and refractive status on children afar three kinds of cycloplegia

Objective To find out the longest effective duration of Mydrin P and Romi eyedrop on cycloplegia,compare the residual accommodation after cycloplegia by Mydrin P eyedrop, 1% Atropine paste and Romi eyedrop, analyze their effect on ametropia. To provide some experimental basis for using cycloplegia adeptly in clinic. Methods Seventy-five children (147eyes) were checked, 4～16 years old with, mean age of 10.12 years old. There are no systemic diseases. The patients were divided into 3 groups: A, 1% Atropine group; B,Romi eyedrop group and C,Mydrin P group. Before and after administration of these eyedrops,ob-jective refraction was checked in hand-hold auto refractor; subjective refraction was checked in phoropter,and retinoscopy refraction was finished. Phoropter was used to check the accommodation response and the residual accommodation respectively by pushup method. Results (1)In Romi eyedrop group,the time of maxi-mum cycloplegia was 60 minutes,the patients can read in the next day; in Mydrin P group,the time was 30 minutes, can read next day. (2) Average residual accommodation at the maximum cycloplegia: A, 1% Atropine group (2.0440±0.95484D),B,Romi eyedrop group (2.2214±0.6952D),C,Mydrin P group (2.6656±0.9999D). The residual accommodation in Romi eyedrop and Atropine groups had no significant difference, In-dependent-samples t Test P 0.05.The residual accommodation in Mydrin P group was stronger than the other two groups,more significant in myopia eyes. (3) The residual accommodation of three groups had no relation-ship with age and refractive status. (4) The results were same in cycloplegic refraction with hand-hold auto re-fractor and phoropter of each group of A, 1% Atropine group,B,Romi eye, drop group and C,Mydrin P group (P 0.05). The difference was 0.33D in autorefraction and phoropter,autorefraction negative. Conelusions (1) The time of maximum cycloplegia effective of Romi eye-drop was 60 minutes, of Mydrin P was 30 min-utes. (2) The residual accommodation in Romi eyedrop and Atropine groups was almost same, the residual ac-commodation in Mydrin-P group was stronger than the other two groups,more significant in myopia eyes. (3)Residual accommodation. Three groups have no relationship with age and refiaction. (4) Romi eyedrop and,Mydrin-P eyedrop can be used in the cycloplegic refraction for children in myopia and hyperopia. Key words: Residual accommodation;  Mydrin-P eyedrop;  Romi eyedrop;  Cycloplegic refraction; Phoropter