The evaluation of left ventricular function in hypertension patients with different left ventricular configuration by four-demensional imaging area strain

Objective To evaluate the left ventricular systolic function of different patients with hypertension by Four-demensional imaging area strain (4D-area strain). Methods Totally 125 hypertension patients and 40 normal subjects (group N) were enrolled. According to Ganan classification, hypertension patients were classified into normal geometry (groups A, n=45), concentric remodeling (group B, n=25), concentric hypertrophy (group C, n=25) and eccentric hypertrophy (group D, n=30). Parameters of left ventricular systolic function, including global area strain (GAS), regional area strain (RAS) and left ventricular end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), cardiac output (CO), ejection fraction (EF), spherical index (Spl), end-diastolic weight (EDMass) were analyzed. Results There was no statistically significant difference among thegroups A, B, C, D, and N in left ventricular EDV, SV and CO (F=0.679, 3.829, 0.600, P>0.05). There were statistically significant differences among ESV, EF, Spl and EDMass (F=3.829, 6.596, 2.653, 6.596, P 0.05). Conclusions 4D-area strain is a convenient and noninvasive method for evaluation of left ventricular systolic function in patients with different patterns of hypertension. Especially, it′s more sensitive in the early detection of left ventricular systolic function. Key words: Ultrasonography; Ventricular function, left; Hypertension