2011•Chinese Journal of NeuromedicineRequires access

Relation between signal transduction pathways of P38 mitogen-activated protein kinase and proliferation and reperfusion of vascular cells

Yanjun Huang, Zheng-hua Liu

Abstract

丝裂原活化蛋白激酶(mitogen-activated protein kinase，MAPK)是广泛表达的丝氨酸/酪氨酸激酶，在真核生物细胞多种信号转导通路中起重要的作用，受多种因素的调控，作用底物多种多样。P38信号通路是MAPK通路中相当重要的一个分支，在炎症、细胞应激、凋亡、细胞周期和生长等多种生理、病理过程中起着重要作用。关键词：衔接蛋白质类，信号转导；细胞增殖；再灌注;P38MAPK 分类号：R743 文献标识码：A 文章编号：1671-8925(2011)08-856-03

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Signal transduction, Mitogen-activated protein kinase, Cell biology, Protein kinase A, p38 mitogen-activated protein kinases, Signal pathway, Kinase, MAPK/ERK pathway