Efficacy of concurrent treatment of three-dimensional conformal radiotherapy with chemotherapy on recurrent esophageal carcinoma after single radiotherapy

Objective To study the efficacy of concurrent treatment of three-dimensional conformal radiotherapy with chemotherapy on recurrent esophageal carcinoma after single radiotherapy. Methods Ninety-four esophageal patients receiving pre-rediaotherapy from December 2014 to May 2015 in Xuchang Central Hospital were divided into two groups. Forty-seven patients cases in control group received single three-dimensional conformal radiotherapy, and 47 cases in study group received concurrent treatment of three-dimensional conformal radiotherapy with chemotherapy. The recent local efficiency rate, 3-year survival rate and death cause were analyzed. Results ① The recent local control rate in observation group was 58.70%, which was higher than that (54.35%) in the control group, but there was no significant difference between the two groups (P>0.05). ②The 3-year survival rate in the observation group was 17.39%, which was higher than that (13.04%) in the control group, but there was no significant difference between the two groups(P>0.05). ③Thirty-eight patients died in the observation group, an 52.63% of the patients died of adverse reactions, which was higher than that (27.50%) in the control group, there was significant difference between the two groups (P 0.05). Conclusions Concurrent treatment of three-dimensional conformal radiotherapy with chemotherapy on recurrent esophageal carcinoma after single radiotherapy is a little bit better than single radiotherapy, but can't improve efficiency of local carcinoma and 3-year survival. The common death-cause is adverse reaction, which should be given high priority in treatment. Key words: Esophageal carcinoma; Radiotherapy; Survival rate; Recurrent; Local control rate; Three-dimensional conformal radiotherapy