Initial study on correlation between C-reactive protein and acute cerebral infarction

Objective To find out the correlation of C-reactive protein (CRP) and acute cerebral infarction, and to provide research data for acute cerebral infarction. Methods 43 cases with acute cerebral infarction were set as the observation group, and 40 healthy people were set as the control group.The CRP level of the observation group and the control group, and CRP level of different infarction volume and neurological function defect degree were compared.The influence factors of CRP level were analyzed with single factor analysis and Logistic regression. Results The CRP level of the observation group was (14.19±2.60)mg/L, which was significantly higher than that of the control group (t=7.453, P<0.05). With the increase of infarction volume, CRP levels increased (t=3.451, 8.534, 5.930, all P<0.05). With the increase of nerve function defect degree, CRP level elevated (t=3.845, 9.077, 6.730, all P<0.05). CRP level and systolic blood pressure, fasting glucose, total cholesterol, fibrinogen were positively correlated (r=0.479, 0.603, 0.508, 0.603, all P<0.05). Cerebral infarction, systolic blood pressure, fasting glucose, total cholesterol and fibrinogen were the influence factors of CRP level. Conclusion There is correlation between C-reactive protein and acute cerebral infarction; detecting CRP level can assist in diagnosis of cerebral infarction.It was favorable to prevent and control the occurrence and progress of acute cerebral infarction. Key words: Cerebral infarction; Neural function defect scale; C-reactive protein