Application of multislice CT scan combined with 99mTC-MIBI-SPECT in the diagnosis of isolation pulmonary nodule lesions

Objective To discuss the applied value of multislice CT scan in combination with 99 MTC-MIBI-SPECT for the diagnosis of isolated pulmonary nodule lesions. Methods 60 patients with solitary pulmonary nodules shadow in the X-ray film from July 2014 to August 2015 in our hospital were selected and detected by spiral CT scanning and 99mTC-MIBI-SPECT imaging.Scan results and pathological examination or surgery were compared, specificity, sensitivity and accuracy of pulmonary nodules were concluded about the method in the differential diagnosis isolation. Results The specificity, sensitivity and accuracy of multislice spiral CT scanning alone were 73.6%, 78.2%, 79.3% respectively; The specificity, sensitivity and accuracy of 99mTC-MIBI-SPECT imaging alone, were 82.6%, 78.2%, 79.3% respectively; The specificity, sensitivity and accuracy of multislice CT scan combined with 99mTC-MIBI-SPECT imaging were 93.3%, 93.2%, 93.8% respectively.The accuracy of combined detection was significantly higher than that of 99mTC-MIBI-SPECT examination(χ2=6.783, P=0.010) or CT scan (χ2=8.012, P=0.008). Conclusion Multislice CT scanning combined with 99mTC-MIBI-SPECT imaging has better effect in diagnosing pulmonary nodule lesions, which is superior to the method alone.The combination method can obviously improve the detection rate of lung nodule lesions, which is, worthy of further promotion. Key words: 99mTC-methoxy isobutyl isonitrile; Tumor avid imaging; Tomography, spiral X-ray machine; Pulmonary nodules; Diagnosis