Detection and clinical significance of C reaction protein in patients with ulcerative colitis

Objective To study the detection and clinical significance of C reaction protein(CRP)in patients with ulcerative colitis(UC).Methods The levels of peripheral blood CRP and blood platelets count(BPC)in patients with UC(n=57) and normal controls group(n=30)were detected and the effects on disease severity were analyzed subsequently.Results The levels of peripheral blood CRP and BPC in active phase group were significantly higher than those in catabasis group(P＜0.05),they were no significant difference between catabasis group and norreal controls group(P＞0.05);the leveh of peripheral blood CRP and BPC in severe stage were significantly higher than those in medium stage(P＜0.05),in medium stage,severe stage they were significantly higher than those in mild stage(P＜0.05,P＜0.01).Conclusion The level of peripheral blood CRP and BPC had important value to judge active phase and severity of UC. Key words: Ulcerative colitis; C reaction protein; Blood platelets count