Clinical Effect on Ulcerative Colitis Patients to C-reaction Protein Level Change

Objective: To investigate the Abstract of blood C-reactive protein (CRP) levels in ulcer disease colitis (UC) in pa- tients with disease activity and severity of the evaluation. Methods :86 cases of patients with UC, as well as 42 cases of healthy controls, the collection of peripheral blood, serum CRP, ESR and other biochemical markers (liver function, kidney function, immune globulin) level of CRP analysis focused on different clinical period of change and To assess the clinical and other indicators related to each other. Results: the activities of UC in patients with serum concentrations of CRP were significantly higher than healthy people (P 0.01). UC patients with severe levels of CRP were significantly higher than moderate UC patients (P 0.05); moderate UC in patients with serum CRP levels were significantly higher than UC patients with mild (P 0.05). Active UC in patients after effective treatment, serum CRP levels were significantly decreased (P 0.05). Analysis found that the activities of UC patients and the severity of serum CRP levels between the positive correlation between(r = 0.91, P 0.01), while the other laboratory indicators (such as ESR, liver function, kidney function, immune globulin), There was no significant correlation (P 0.05). Conclusion: CRP levels can be accu- rately reflect the severity of clinical patients with UC, for the clinical treatment and control of disease development, prognosis, as well as provide important theoretical basis.